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Innovative Protonentherapie-Technik am Westdeutschen Zentrum für Protonentherapie in Essen

Job offer:
Research Assistant at BMFTR-funded project “UncovRT”

We are seeking a PhD candidate in the field of computational medical physics (75%, TV-L E13, 3 years) to join our BMFTR-funded research project on molecular mechanisms of side effects after cranial proton therapy.

from 1 August 2026

The project will assess neurocognitive and neurovascular late effects in pediatric proton therapy. UncovRTUncover molecular mechanisms of side effects after cranial Radiation Therapy to improve quality of life for long term survivors of brain cancer

Specifically, we plan to refine and expand the existing predictive models for contrast-enhancing lesions in pediatric patients with brain tumors who have undergone proton therapy. The research will be conducted within the framework of a national consortium. The opportunity to pursue a doctorate is offered. The doctorate is embedded in medical and medical physics research at the WPE and in the regional research landscape of the Ruhr universities, in particular the DFG-funded research training group 3043 AMTEC-PRO – Advanced Methods and Technologies for Proton Therapy.

West German Proton Therapy Centre Essen
Am Mühlenbach 1, 45147 Essen


Job Scope: 75 Percent
Start: 01.08.2026

Working at the University Medical Centre Essen

As a maximum-care university hospital with a capacity of around 1,300 beds, we treat 225,000 patients a year with over 6,000 employees in 26 clinics, 23 institutes and specialist centres. Our hospital offers medical care, state-of-the-art diagnostics and comprehensive treatment to the highest international standards. In addition, we offer a comprehensive range of research and teaching services at an internationally competitive level.

Absprache zwischen zwei Mitarbeitenden des WPE auf dem Flur
Ein Arzt des WPE im Anamnesegespräch mit einem neuen männlichen Patienten mit Prostatakrebs

Working in the heart of the Ruhr region

In Essen, in the heart of the Ruhr region and the green capital of Europe in 2017, the WPE’s Particle Therapy Clinic offers a challenging field of work in the application of state-of-the-art proton therapy for the effective yet particularly gentle treatment of tumor diseases. Since 2013, the WPE has been successfully treating outpatients with CNS tumors, head and neck tumors, sarcomas, prostate carcinomas and childhood tumors with proton therapy. Since its opening, the WPE has acquired an excellent reputation recognized worldwide. Numerous collaborations at national and international level are proof of the high therapeutic and scientific standard of our work. The result: our patients come to us in Essen not only from all over Germany, but also from many other European and non-European countries. That is why we are looking for you to join our team.

Working at WPE

At our West German Proton Therapy Centre Essen (WPE), under the direction of Prof. Beate Timmermann, we offer state-of-the-art radiation therapy for tumor diseases using protons. The centerpiece of the facility is a 230 MeV cyclotron. The four treatment rooms contain three gantries that can be rotated through 360 degrees and a fixed-beam room with 2 fixed beam lines. Each of the rotating gantries weighs approximately 120 tons and yet ensures an accuracy of up to 0.25 degrees. The Pencil Beam Scanning method (PBS) and a state-of-the-art therapy planning system are used for Intensity Modulated Proton Therapy (IMPT). This means that the entire craniospinal axis (CSA, includes the brain and spinal canal) can be routinely irradiated in the WPE for tumors of the central nervous system (CNS). The availability of IMPT also enables a simultaneous integrated boost (SIB) – i.e. simultaneous boost irradiation.

Zwei Personen besprechen den Therapieplan eines Hirntumors anhand von seitlichen MRT-Aufnahmen
UncovRT-Logo

“UncovRT”

Your Responsibilities

  • Conducting Monte-Carlo simulations of proton treatment plans
  • Refinement of predictive models for risks of adverse events in proton therapy
  • Cooperation with study nurses and the medical team in data collection and data review
  • Coordination with partners at other locations of the consortium
  • Oral presentations of research results and preparation of scientific publications
Hochmodernes Protonen-Bestrahlungsgerät am Westdeutschen Protonentherapiezentrum in Essen
Zwei Mitarbeitende besprechen die Bilder eines Ultraschallgeräts

Your Qualifications:

  • Completed Master’s degree in medical physics or physics
  • Background in medical imaging or radiotherapy.
  • Advanced IT and programming skills (e.g., Python, MATLAB)
  • Good analytical skills and strong knowledge of statistical analysis
  • English language skills at least on B2 level (German is a plus).
  • Desirable, but not madatory: Dose simulation for radiotherapy & Radiation response modeling

Look forward to

  • A challenging, diverse and application-oriented research in a highly qualified, interdisciplinary, open-minded and collegial team in one of Europe’s largest centres for proton therapy as well as practical experience in the physics team.
  • You will work closely with a team of radiation therapy experts
  • You will be part of a university, interdisciplinary environment with diverse scientific development opportunities
  • Fair pay in accordance with the collective wage agreement (TV-Länder)
Technische Vorbereitung zur Protonentherapie am Westdeutschen Protonentherapiezentrum

Apply now! And become a research assistant at the UncovRT-Project!

Prof. Dr. Christian Bäumer
West German Proton Therapy Centre Essen (WPE)
Universitätsklinikum Essen
Hufelandstraße 55
45147 Essen, Germany

Further information:

Applications from people of all genders are expressly welcome. Applications from women will be given preferential treatment in accordance with regulations. Measures to promote gender equality in science and, if necessary, to create a more family-friendly workplace are supported.

Please note that applications from suitable severely disabled persons are welcome.

Proton therapy

Planungsbild für eine Protonenbestrahlung

Radiation therapy with protons is considered to be particularly gentle. We have summarized the background and mode of action of proton therapy on this page.

Tumours treatable

Manche Patienten mit ZNS-Tumoren entwickeln Rückfälle. Foto: AdobeStock/Gorodenkoff

Thanks to our expertise and intensive collaboration with the various disciplines at Essen University Hospital, we are able to irradiate a large number of tumors with proton therapy at the WPE.

Interdisciplinarity

Grugalauf 2024

At the West German Proton Therapy Centre, different professional groups work together to provide the best therapy for patients. Various team events are held together.